Colchicine to be investigated as possible Covid-19 treatment

The scientists behind the trial said inflammation plays a major role in Covid-19 and treatment with dexamethasone, another anti-inflammatory drug. — AFP pic
The scientists behind the trial said inflammation plays a major role in Covid-19 and treatment with dexamethasone, another anti-inflammatory drug. — AFP pic

NEW YORK, Nov 27 — Colchicine, a commonly used anti-inflammatory drug, will be investigated as a possible treatment for Covid-19 in the Randomised Evaluation of Covid-19 Therapy (RECOVERY) trial, the study website posted today.

The RECOVERY trial, which is the world’s largest clinical trial of treatments for patients hospitalised with Covid-19, will randomly allocate at least 2,500 patients recruited to receive colchicine. “Colchicine is an attractive drug to evaluate in the RECOVERY trial as it is very well understood, inexpensive and widely available,” SAID Oxford University Professor Peter Horby, who is co-chief investigator for the trial.

Colchicine costs about US$124 (RM505) for 30 capsules on the drugs.com website.

The scientists behind the trial said inflammation plays a major role in Covid-19 and treatment with dexamethasone, another anti-inflammatory drug, has already shown that it can reduce deaths in the most severely ill patients.

Earlier this month, one of Britain’s biggest trials also evaluated painkiller aspirin as a possible treatment for Covid-19, assessing whether it might reduce the risk of blood clots in people with the disease.

Other treatments being tested in the RECOVERY trial include common antibiotic azithromycin and the Regeneron antibody cocktail that was used to treat US President Donald Trump’s Covid-19 symptoms. — Reuters

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